Experts have found the first mention of marijuana as a healing product in the 2,600 BC pharmacopeia in China. For thousands of years, different cultures have independently discovered the medical utility of the cannabis plant. People have used it in folk medicine, natural medicines, plant-based medication and as a cure-all in multiple cultures. The history of cannabis in medicine is quite extensive thanks to its hundreds of beneficial ingredients and numerous subspecies.
At the same time, thousands have experimented with the THC-rich cultivars of the plant for exploring spiritualism. Several controversies have risen and fallen as cannabis gradually left the alternative medicine world and stepped into the flower-power lifestyle of the late 60s and early 70s. Amidst the debates, it became a highly tabooed substance that garnered skepticism from all over the world. Consumption of marijuana in all forms saw the imposition of strict regulations in the US during this time. That restricted the research of cannabis and cannabinoids on the human system.
Why is there a sudden surge of researches on the health effects of cannabis?
Only recently, there has been some relaxation in a few states about the consumption of medical marijuana. As a result of the review of regulatory rules, new studies on the effects of the phytocannabinoids on human health began. Researchers from all over the US have been publishing credible and exciting findings of the healing impact of cannabidiol and other Phyto-compounds that come from the cannabis plant. Apart from these studies, many methods have successfully created cannabis plants with the minimal quantity of tetrahydrocannabinol (THC), the compound responsible for its hallucinogenic effects.
The discovery of the endocannabinoid system (ECS) in the 1990s has led to groundbreaking research on the analgesic properties of the herb. In the next two decades, subsequent studies on the ECS has shown over 27 diseases that bear a direct link to it including pain, inflammation, anxiety, panic, depression, autism, PTSD, obesity, cancer, ischemia, schizophrenia, anorexia, Parkinson’s, Tourette’s syndrome, Huntington’s and psychosis. Extensive research is ongoing on the different disorders and the effectiveness of CBD treatment.
What makes marijuana a special gift of nature?
Since the first mention of its medical uses in the 2600 BC, people have been using marijuana to treat multiple physiological, emotional and physical illnesses. People have been exploring its benefits, but only recently, medical research has achieved some of the most significant breakthroughs including the treatment of Alzheimer’s, Huntington’s, Parkinson’s, childhood seizure disorders, Multiple Sclerosis, tumorigenesis, and cancer. Most of these studies involve the use of CBD only or a mix of CBD with trace amounts of THC. Most manufacturers use hemp extract for sourcing the phytocannabinoid to minimize the presence of THC.
In addition to the ones we have mentioned above, the cannabis plant contains over 400 different phytocannabinoid compounds that have extensive medical benefits. In fact, CBD accounts for up to 40% of the plant’s natural extract. The cannabis oils, balms, salve and lotions you can see on cannabinoids from Global Cannabinoids contain purified versions of the same. All other phytocannabinoid compounds present in these products are direct derivatives of the natural cannabigerol-type plant compounds. These compounds are present in the plant extracts from various cannabis species and in hemp as well.
How does CBD interact with your brains and nerves?
CBD does not have psychotropic effects like THC. In patients with acute pain, the treatment with CBD extracts containing trace amounts of THC showed alleviation of acute, visceral, chronic and inflammatory pain. Our brain has CB1 receptors in the basal ganglia and substantia nigra. The placements are critical for the mediation of reduction of pain when the cannabinoid molecules bind the CB1 receptors. The activation of these receptors in the different areas of the brain causes the excitation of specific signaling pathways that inhibit the neurotransmission. This mechanism can not only result in the redressal of pain, but it can also stop seizures and reduce neuronal degradation caused by neurodegenerative diseases.
CBD usually interacts with the CB2 receptors in the neuronal system. This interaction is a little more complicated than the phytocannabinoid and CB1 interaction, but it mediates the pain and inflammation reduction pathways as well. Moreover, the interaction of CB2 with CBD also reduces chronic and acute neuroinflammation in human beings. Another study shows that, in more copious amounts, CBD can counter the psychoactive effects of THC. In fact, several cannabis users who ingest CBD and THC together, report the partial antagonistic impact of CBD against THC molecules.
The use of phytocannabinoids to treat neuronal disorders
As a result, CBD is highly effective in the treatment of neurodegenerative diseases like Alzheimer’s. In the case of Alzheimer’s Disease, the cannabinoids act as neuroprotective agents. It reduces the inflammation by directly binding with the CB1 and CB2 receptors in critical locations of the brain. The treatment of MS using CBD has a long medical history. The mutual interaction of the molecule and the neurodegenerative disease with the ECS signaling system makes CBD one of the most effective agents for the treatment of the same. People suffering from MS experience a decrease in the frequency of MS symptom relapses and the phytocannabinoids can even slow the progression of the disease. Several new studies on the effects of marijuana compounds on brain trauma, brain ischemia, and tumors. Whether it is PTSD or a cerebral stroke, the correct use of CBD can lessen the symptoms and provide long-term relief to the sufferer.
More reasons for you to try CBD
CBD has next to no toxicity in the human users in all ingested and topical forms. Whether you are using CBD soft gel capsules, oil, salve, balm, or patches, you do not have to worry about toxicity and overdosing since human beings have a high tolerance of the compound. Additionally, no marketed CBD product has high THC content unless the manufacturer mentions it on the label. The lipophilic properties of CBD allow it to cross the blood-brain barrier quite easily. It passes out with urine and has a half-life of 9 hours.